Glossary – Luminex IS Version 2.3 User Manual

Page 103

Advertising
background image

PN 89-00002-00-110 Rev. B

93

Glossary

agglutination

The coalescing of small particles that are suspended in solution;
these larger masses are then (usually) precipitated.

ambient temperature

The temperature of the surrounding environment.

analyte

A substance that is detected through assay analysis. Each test or bead
set will test for a specific analyte.

analyzer

This term is used to refer to the Luminex 200 analyzer.

APD

Avalanche Photo Diode; Measures the excitation emission intensity
of the color coding classification dye mixtures inside the
microsphere and the amount of light scattered as particles pass by the
lasers.

background (noise)

That portion of a bead set result that can be attributed to excess
reporter molecules in the solution, nonspecific binding, or
fluorescent spillover from another fluorochrome.

batch

A group of samples that are processed using a selected template.

bead

Shorthand terminology for an xMAP microsphere.

bead set

a set of xMAP microspheres that have a uniquely identifiable ratio of
two classification dyes. The unique ratio is identified by a unique
spectral address.

calibration

A process used to normalize the settings for the reporter channel,
both classification channels, and the doublet discriminator channel
for the Luminex System. Calibration ensures optimal and consistent
microsphere classifications and reporter readings.

calibrators

xMAP microspheres used to normalize the settings for the reporter
channel, both classification channels, and the doublet discriminator
channel for the Luminex System.

Advertising