General guidelines, Biological samples, Bead handling – Luminex xPONENT 4.0 SP1 User Manual

Page 15: Limitations

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Introduction

General Guidelines

Modifying or deleting xPONENT

®

system files may cause degradation to system

performance. You can repair modified or deleted xPONENT system files by uninstalling
and re-installing the xPONENT software.

Use of unauthorized third party software with xPONENT software may result in corruption
or failure of the xPONENT software. Use third party software at your own risk.

If using a screen saver on the xPONENT system, be aware that xPONENT will prevent it
from activating. A dialog box will display each time xPONENT is launched, recommending
that the screen saver and any power management settings are turned off.

This system contains electrical, mechanical, and laser components that, if handled
improperly, are potentially harmful. In addition, biological hazards may be present during
system operation. Therefore, we recommend that all system users adhere to standard
laboratory safety practices. The protection provided by the equipment may be impaired or
the warranty voided if Luminex FLEXMAP 3D™ is used in a manner not specified by the
instructions or by Luminex Corporation.

Biological Samples

Human and animal samples may contain biohazardous infectious agents. Where
exposure to potentially biohazardous material, including aerosol, exists, follow appropriate
biosafety procedures and use personal protective equipment - gloves, gowns, laboratory
coats, face shields, or mask and eye protection - and ventilation devices. Observe all
local, state, and federal biohazard handling regulations when disposing of biohazardous
waste material.

Bead Handling

xMAP beads come in various configurations. Avoid excessive agitation of the product to
reduce foaming and surface precipitation. The xMAP beads will settle if left undisturbed.
Always ensure that the xMAP beads are homogeneously resuspended prior to dispensing.
The uncoupled xMAP beads are not monodispersed and tend to aggregate until coated.
Multiple pipetting from the original container may affect bead concentrations. Protect the
xMAP beads from light at all times. Store xMAP beads at 2 to 8°C.

NOTE:

Refer to the product information sheet that accompanies your
xMAP beads or assay for additional information.

Limitations

xMAP beads are susceptible to photobleaching; photobleaching effects are cumulative.
Minimize exposure of xMAP beads to light during your development and manufacturing
phases to maintain product integrity.

xMAP beads are hydrophobic in the aqueous medium provided and will settle if left
undisturbed. Resuspend prior to dispensing.

Do not use this product with strong organic solvents. For information on specific
compatibility, visit the Luminex Technical Support website at www.luminexcorp.com. From
the main page, click Support, then FAQs.

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