Luminex xPONENT for MAGPIX - Manual (Page 16)

CAUTION: Modifying or deleting xPONENT system files may cause
degradation of system performance. You can repair modified or
deleted xPONENT system files by uninstalling and re-installing
the xPONENT software. Luminex recommends that you contact
Technical Support before uninstalling and re-installing xPONENT
CAUTION: Using unauthorized third-party software with xPONENT software
may result in corruption or failure of the xPONENT software. Use
third-party software at your own risk.
CAUTION: If you are using a screen saver on the PC on which xPONENT is
installed, xPONENT prevents it from activating. A dialog box
displays each time xPONENT is launched, recommending that
the screen saver and any power management settings be turned
off.
CAUTION: This system contains electrical and mechanical components that,
if handled improperly, are potentially harmful. In addition,
biological hazards may be present while operating the system.
Luminex recommends that you adhere to standard laboratory
safety practices. The protection provided by the equipment may
be impaired or the warranty voided if Luminex MAGPIX is used
in a manner not specified by the instructions or by Luminex
Corporation. Refer to the Luminex
® MAGPIX ™ Installation and
Hardware User Manual for detailed safety information.
Biological Samples
CAUTION: Human and animal samples may contain biohazardous
infectious agents. Where exposure to potentially biohazardous
material—including aerosol—exists, follow appropriate biosafety
procedures and use personal protective equipment such as
gloves, gowns, laboratory coats, face shields, or mask and eye
protection. Use ventilation devices. Observe all local, state, and
federal biohazard handling regulations when disposing of
biohazardous waste material.
Dilute concentrated biological samples, such as plasma or serum, at least 1:5 with reagents
as part of assay setup or as a final dilution step to reduce the chance of system clogs. If you
are running a MagPlex
® kit, follow the dilution instructions in the kit’s product insert.
Bead (Microsphere) Handling
MagPlex beads come in various configurations. To reduce foaming and surface precipitation,
avoid agitating the beads until you are ready to vortex and use them. The beads will settle
and must be resuspended by vortexing before use. In addition:
• Multiple pipetting from the original container may affect bead concentrations.
• Protect MagPlex beads from light at all times to prevent photobleaching. Photobleaching
effects are cumulative. To maintain the integrity of the beads, minimize their exposure to
light during your development and manufacturing phases.
• Store MagPlex beads at 2°- 8°C.
Introduction
3