MEGUIAR'S C2000 - Manual (Page 8)

C2000, Mirror Glaze Professional Detailing Clay (Mild)
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reproduction mg/kg/day
Silicon dioxide Ingestion Not toxic to
development Rat NOAEL
1,350
mg/kg/day during organogenesis
Talc Ingestion Not toxic to
development Rat NOAEL
1,600 mg/kg during organogenesis
Pigments Ingestion Not toxic to female
reproduction Rat NOAEL
1,000
mg/kg/day premating & during
gestation
Pigments Ingestion Not toxic to male
reproduction Rat NOAEL
1,000
mg/kg/day 42 days
Pigments Ingestion Not toxic to
development Rat NOAEL
1,000
mg/kg/day premating & during
gestation
Target Organ(s)
Specific Target Organ Toxicity - single exposure
Name Route Target
Organ(s) Value Species Test result Exposure
Duration
Calcium
Carbonate Inhalation respiratory
system All data are
negative Rat NOAEL 0.812
mg/l 90 minutes
Silicon
dioxide Data not available
or insufficient for
classification
Talc Data not available
or insufficient for
classification
Pigments Data not available
or insufficient for
classification
Specific Target Organ Toxicity - repeated exposure
Name Route Target
Organ(s) Value Species Test result Exposure
Duration
Calcium
Carbonate Inhalation respiratory
system Some positive
data exist, but the
data are not
sufficient for
classification Human NOAEL Not
available occupational
exposure
Butene,
homopolymer
(products
derived from
either/or But-
1-ene/But-2-
ene) Inhalation respiratory
system Some positive
data exist, but the
data are not
sufficient for
classification Rat NOAEL 0.07
mg/l 2 weeks
Butene,
homopolymer
(products
derived from
either/or But-
1-ene/But-2-
ene) Inhalation liver Some positive
data exist, but the
data are not
sufficient for
classification Rat NOAEL 0.7
mg/l 2 weeks
Talc Inhalation pneumoconiosis Causes damage to
organs through
prolonged or
repeated exposure Human NOAEL Not
available occupational
exposure
Talc Inhalation pulmonary Some positive Rat NOAEL 18 113 weeks