Waters PoraPak RXN Cartridges - Manual

[ Care and Use ManUal ]
PoraPak ™ RXN Cartridges and Bulk Care & Use 1
Contents
I. Common ApplICAtIons for CleAnup
II. protoCols
III. produCt GuIdelInes
porApAk rXn CArtrIdGes
IntroduCtIon
Waters PoraPak ™ Rxn cartidges and bulk are a family of polymer-based
chromatography products for designed for cleanup of synthetic reactions.
PoraPak Rxn products are available in two chemistries:
• PoraPak Rxn CX, a strong cation-exchange sorbent
• PoraPak Rxn RP, a reversed-phase sorbent.
PoraPak Rxn sorbents are based on copolymers that exhibit the
following properties:
• Hard material that does not develop increasing
back pressure with flow.
• Little swelling or shrinking across a range of
solvents and pH extremes.
• Low hydraulic resistance enables flow by gravity.
• pH extreme tolerance without dissolution or hydrolysis,
both limitations of silica-based sorbents.
This combination of physical and chemical properties makes PoraPak Rxn
cartridges ideal for synthesis cleanup. The polymers characteristics and
particle size maintain gravity, pressure - or vacuum - assisted flow; even
when reaction mixtures contain precipitate that may contribute additional
resistance to flow. The sample will still pass through the cartridge. The
polymer used in PoraPak Rxn products is resistant to shrinking or swelling
in the organic solvents typically used in synthetic reactions.