Labconco Biological Safety Cabinets 34610 Series User Manual

Page 19

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All Purifier Series Logic Biosafety Cabinets operate using the following
principles:

• Filtration and retention of particulates by High Efficiency Particulate

Air (HEPA) filter(s)

• Laminar airflow

• Directional airflow

The major components in a Biosafety Cabinet are:

• The HEPA filter(s) or optional ULPA filters

• The motor/blower to force air through the Cabinet

• Cabinet air intakes (grilles), ductwork and air balance controls

HEPA Filters

HEPA filters are disposable, dry-type particulate filters. The filter material or
media is typically made of borosilicate microfibers formed into a thin sheet,
in a process similar to the production of paper. This sheet is folded, or pleated
to increase its surface area. The pleats are held in place by aluminum
diffusers or by beads of glue that add rigidity to the media pack. The pack is
then set into a frame, and sealed as shown in Figure 4-1.
The HEPA filter manufacturer establishes the efficiency of the filter by
challenging it with an aerosol of known particle size. The number of particles
that penetrate the filter are quantified, and this establishes the efficiency of
the filter. Thus, the filters used in the Logic Series Cabinets are at least
99.99% efficient in removing particles 0.3 micron.

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