MEGUIAR'S M80 - Manual (Page 9)

M80, Speed Glaze (13-171C): M8001, M8032
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1-methyl-2-pyrrolidone In vivo Not mutagenic
1-methyl-2-pyrrolidone In Vitro Some positive data exist, but the data are not
sufficient for classification
Glycerin No data available
Processed oil In Vitro Not mutagenic
Processed oil In vivo Not mutagenic
Siloxanes and silicones, di-Me No data available
Conditioners No data available
2-Methoxyethanol In Vitro Not mutagenic
2-Methoxyethanol Inhalation Not mutagenic
Carcinogenicity
Name Route Species Value
Aluminium oxide Inhalation Not carcinogenic
Naphtha (petroleum), hydrotreated
heavy Dermal Some positive data exist, but the data
are not sufficient for classification
Naphtha (petroleum), hydrotreated
heavy Inhalation Some positive data exist, but the data
are not sufficient for classification
Distillates (petroleum), hydrotreated
middle Dermal Mouse Some positive data exist, but the data
are not sufficient for classification
1-methyl-2-pyrrolidone Inhalation Rat Not carcinogenic
Glycerin Ingestion Mouse Some positive data exist, but the data
are not sufficient for classification
Processed oil No data available
Siloxanes and silicones, di-Me No data available
Conditioners No data available
2-Methoxyethanol No data available
Reproductive Toxicity
Reproductive and/or Developmental Effects
Name Route Value Species Test result Exposure Duration
Aluminium oxide No data available
Naphtha (petroleum),
hydrotreated heavy Inhalation Not toxic to
reproduction and/or
development NOAEL
2.356 mg/l
Distillates
(petroleum),
hydrotreated middle No data available
1-methyl-2-
pyrrolidone Inhalation Some positive
developmental data
exist, but the data are
not sufficient for
classification Rat LOAEL 0.68
mg/l during gestation
1-methyl-2-
pyrrolidone Dermal Toxic to reproduction
and/or development NOAEL 237
mg/kg/day
1-methyl-2-
pyrrolidone Ingestion Toxic to female
reproduction Rat LOAEL 50
mg/kg/day 2 generation
1-methyl-2-
pyrrolidone Ingestion Toxic to male
reproduction Rat LOAEL 50
mg/kg/day 2 generation
1-methyl-2-
pyrrolidone Dermal Toxic to development Rat NOAEL 237
mg/kg/day during organogenesis
1-methyl-2-
pyrrolidone Ingestion Toxic to reproduction
and/or development LOAEL 50
mg/kg/day
1-methyl-2-
pyrrolidone Ingestion Toxic to development Rat NOAEL 160
mg/kg/day 2 generation
Glycerin Ingestion Not toxic to female
reproduction Rat NOAEL
2,000
mg/kg/day 2 generation
Glycerin Ingestion Not toxic to male Rat NOAEL 2 generation