C.B.S. Scientific FCU-1000 - Manual (Page 4)

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1.3 System Overview
The 3-D Flow Chamber Device is a specialized laminar flow chamber that enables the unique ability
to quantitate cellular motility through a semi-permeable membrane in the presence of shear stress.
Relevant applications for the 3-D Flow Chamber Device include transmigration, chemotaxis, vascular
permeability, and complex in vitro modeling of 3D cell cultures such as the blood brain barrier. Fur-
ther, it can be used to hold material coupons in place of the membranes for analysis of biofilm activity.
1.4 System Contents
The following components ship with the 3-D Flow Chamber Device.
Complete System Includes:
• Flow Chamber Device with 3 reservoirs
• 3 upper membrane inserts
• 3 lower membrane inserts
• Tubing and connectors
• Carrying tray
• Respirator to allow gas exchange and bubble escape