3first use of the mea switch, 1 welcome to the mea s4/2 – Multichannel Systems MEAS42+MEASwitchUSB Manual User Manual

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First Use of the MEA Switch

3.1 Welcome to the MEA S4/2

The MEA S4/2 allows to acquire data from 240 single channels from four 60 channel amplifiers.
Selected channels are combined to a single “Electrode Raw Data” stream that is delivered to the
MC_Card or an USB based data acquisition system by a 68-pin MCS high grade cable. This is useful
if you do not need all 60 electrodes on a MEA, for example, because the cell culture or the slice
does not cover the whole MEA, but rather single electrodes.

The channel selection is mutually exclusive, that means, if you pick channel 21 on one MEA,
you cannot select channel 21 on the other pair. The MEA S4/2 is software-controlled by the
program MEA_Switch via USB port.

The MEA S4/2 does not replace a Signal Grounding unit. That means, the channels that are not
selected are only removed from the input data stream, but they are not grounded. If you have
bad electrodes that produce noise, the noise can still interfere with your input signals.

You need an external power supply for operating the MEA S4/2, for example, the PS40W.

The following pictures show the rear panel of a MEA S4/2, and a standard MEA S4/2 connected
to four MEA amplifiers.

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