Penn-Century MSA-250-M for Mouse - Manual (Page 4)

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KEY FEATURES:
MicroSprayer® Aerosolizer (liquid) - Model IA-1C
Requires FMJ-250
High Pressure Syringe
§ The Penn-Century MicroSprayer® Aerosolizer and FMJ-250 High Pressure Syringe are
the only commercially available air-free intratracheal aerosol delivery technology.
§ They can be used to administer precise doses of aerosol for intratracheal, intranasal or
other in vivo or in vitro applications.
§ The devices have been shown to successfully administer a wide range of pharmaceutical and
biologic agents, as well as toxicological, bacterial and viral materials.
§ The MicroSprayer® Aerosolizer can administer liquids and liquid suspensions/solutions,
including nanoparticle and microparticle solutions.
§ The MicroSprayer® Aerosolizer - Model IA-1C is made of flexible, 23-gage stainless
steel tubing and other chemically resistant components, and is designed to be sterilized and re-
used.
§ The MicroSprayer® Aerosolizer does not have a luer hub. It can only be operated with
Penn-Century’s patented FMJ-250 High Pressure Syringe.
§ Standard lengths of the device are typically made with a 120-degree bend to permit
the user to keep their hand out of the line of sight when viewing the epiglottis.
§ For intratracheal use, the length of portion that is inserted into the trachea is designed to
reach from the incisors to above the carina. For use in mouse, the intratracheal portion is 1.25”
after the bend. For use in rat, it is 2” after the bend.
§ Custom lengths are available for straight, longer or shorter applications, and for
insertion into the trachea or into the lung via an endotracheal tube or bronchoscope.
§ For best results, and to avoid injury to the animal, the tip of the MicroSprayer®
Aerosolizer must be positioned so that the tip is near to – but not touching the carina.
§ Particle size range: Mass Median Diameter of 16-22 µm (microns) NOTE: Particles
analyzed with water using laser defraction method.
§ The MicroSprayer® Aerosolizer can be safely cleaned with hot water or any organic
solvent, autoclave or ultrasonic cleaner, and most, but not all, disinfectants. It is meant to be
sterilized and re-used.