Integra LifeSciences Collagen Wound Dressing, HeliTape, HeliCote, HeliPlug - Manual (Page 5)

Adverse Reactions
• Adverse reactions reported with another microfibrillar collagen
hemostatic agent that were possibly related to its use were
adhesion formation, allergic reaction, foreign body reaction and
subgaleal seroma (report of a single case).
• Since the wound dressings are collagen-based products,
adverse reactions experienced with another microfibrillar
collagen may be related.
• The Absorbable Collagen Wound Dressings for Dental Surgery
differ substantially in source, method of processing, and purity
from other microfibrillar and macrofibrillar forms of collagen
commercially distributed for hemostatic and wound care
applications.
Instructions
1. A sufficiently large Absorbable Collagen Wound Dressing should
be selected so as to completely cover the oral wound. The wound
should be rinsed clean and excess fluid removed. The dressing
should be applied over the wound and held in place with
moderate pressure. The period of time necessary to apply
pressure will vary with the degree of bleeding. In general, two to
five minutes should be sufficient to achieve hemostasis.
2. At the end of the procedure, the Absorbable Collagen Wound
Dressing can be removed, replaced or left in situ. If desired,
the Absorbable Collagen Wound Dressing can be covered
with a periodontal packing to help hold the sponge in place. The
Absorbable Collagen Wound Dressing may be left in situ, when
necessary. However, the dentist should remove any excess
dressing prior to wound closure.
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