Klipsch Reference Premiere RP-500SA II Two-Way Dolby Atmos Elevation/Surround Speakers (Ebony, Pair) - Manual (Page 10)

The only thing you should ever need to do to your speakers is dust them
occasionally. Never apply any abrasive or solvent-based cleaner or any
harsh detergent. You can clean the grilles with the brush attachment of
a vacuum cleaner.
CARE AND CLEANING
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