Fluke 9112A - Manual (Page 44)

MATERIAL SAFETY DATA SHEET
MSDS No: 350 Date Prepared: 03/24/1992 Current Date: 7/26/2002
Last Revised: (03/20/2002)
10. STABILITY AND REACTIVITY
CHEMICAL STABILITY: Stable under conditions of normal use
CHEMICAL INCOMPATIBILITIES: Avoid contact with strong acids.
CONDITIONS TO AVOID: None
HAZARDOUS DECOMPOSITION PRODUCTS: None
HAZARDOUS POLYMERIZATION: Not applicable
11. TOXICOLOGICAL INFORMATION
TOXICOLOGY
CMS wools have been tested for their biopersistence using methods devised by the European Union. The results from
these studies exonerate CMS wools from carcinogen classification under the criteria listed in Nota Q of European
Commission Directive 97/69/EU.
In a lifetime carcinogenicity test, rats were exposed by inhalation for two years (5 days a week; 6 hours a day) to CMS
fibers at 200 WHO fibers/ml. There was neither fibrosis nor carcinogenic response; only reversible cellular changes
were seen. Further, subchronic inhalation studies on rats with CMS fibers at concentrations of 150 fibers (>20 µm long)
per ml for 90 days with follow up to 1 year showed neither inflammation nor cell proliferation. All parameters studied
returned rapidly to baseline levels on cessation of exposure.
After-service, CMS wools may contain crystalline phases including some forms of silica. (See Section 16) However,
CMS fibers heated to 1000°C for 2 weeks were not cytotoxic to macrophage-like cells at concentrations up to 320
µg/cm
2 . In the same test, samples of pure crystalline quartz were significantly active at 20 µg/cm 2 .
EPIDEMIOLOGY
This material has not been the subject of an epidemiology study.
NOTE
Neither the International Agency for Research on Cancer (IARC) nor the National Toxicology Program nor any other
U.S. regulatory or classification entity has evaluated CMS wool. Superwool products are members of a family of
materials whose properties are distinct in several ways from other man-made mineral fibers. In October 2001 IARC re-
reviewed Man-Made Vitreous Fibers and “elected not to make an overall evaluation of the newly developed fibers” [such
as CMS wool] but recognized that “those that have been tested appear to have low carcinogenic potential in
experimental animals.”
While CMS wool is an inert material that does not react with the skin, exposures may cause temporary mild mechanical
irritation to the eyes, skin, nose and/or throat (for First Aid Measurers, see Section 4). Proper handling practices and
the use of protective clothing (see Section 8) can minimize irritation.
12. ECOLOGICAL INFORMATION
No adverse effects of this material on the environment are anticipated.
13. DISPOSAL INFORMATION
WASTE MANAGEMENT
To prevent waste materials becoming airborne, a covered container or plastic bagging is recommended.
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