Document Outline

• Table of contents
• Table of figures
• 1 Introduction
  • 1.1 Instrument description
  • 1.2 Intended use
  • 1.3 Safety instructions
    • 1.3.1 General notes on safety
    • 1.3.2 Electrical safety
    • 1.3.3 Tubing and capillary connections
    • 1.3.4 Flammable solvents and chemicals
    • 1.3.5 Recycling and disposal
  • 1.4 Symbols and conventions
• 2 Overview of the instrument
  • 2.1 Front
  • 2.2 Rear
  • 2.3 Feed-throughs for capillaries and cables
• 3 Installation
  • 3.1 Setting up the instrument
    • 3.1.1 Packaging
    • 3.1.2 Checks
    • 3.1.3 Location
  • 3.2 Capillary connections in the IC system
  • 3.3 Removing the handle
  • 3.4 Removing transport locking screws
  • 3.5 Connecting the drainage tubing and leak sensor
    • 3.5.1 Installing the drainage tubing
    • 3.5.2 Connecting the leak sensor
  • 3.6 Column thermostat
  • 3.7 Connecting the eluent bottle
  • 3.8 Connecting the eluent degasser
  • 3.9 Installing the high-pressure pump
  • 3.10 Installing an inline filter
  • 3.11 Installing the pulsation absorber
  • 3.12 Injection valve
  • 3.13 Suppressor
    • 3.13.1 Inserting the rotors
    • 3.13.2 Connecting the suppressor
      • 3.13.2.1 Installing the eluent path
      • 3.13.2.2 Connecting the regeneration solution
      • 3.13.2.3 Connecting the rinsing solution
  • 3.14 Peristaltic pump
    • 3.14.1 Installing the peristaltic pump
    • 3.14.2 Mode of operation for the peristaltic pump
  • 3.15 Installing the detector
  • 3.16 Connecting the sample degasser (optional)
  • 3.17 Installing the high-pressure gradient module
  • 3.18 Connecting the instrument to a computer
  • 3.19 Connecting the instrument to the power supply
  • 3.20 Initial start-up
  • 3.21 Connecting and rinsing the guard column
  • 3.22 Connecting the separation column
  • 3.23 Conditioning
• 4 Operation
• 5 Operation and maintenance
  • 5.1 IC system
    • 5.1.1 Operation
    • 5.1.2 Care
    • 5.1.3 Maintenance by Metrohm Service
    • 5.1.4 Shutting down and starting back up
  • 5.2 Capillary connections
  • 5.3 Servicing the door
  • 5.4 Column thermostat – Replacing the capillaries
  • 5.5 Handling the eluent
    • 5.5.1 Manufacturing eluent
    • 5.5.2 Changing the eluent
  • 5.6 Servicing the eluent degasser
  • 5.7 Notes on operating the high-pressure pump
  • 5.8 Servicing the high-pressure pump
  • 5.9 Servicing the inline filter
  • 5.10 Servicing the pulsation absorber
  • 5.11 Injection valve
  • 5.12 Suppressor
    • 5.12.1 Notes for operating the suppressor
    • 5.12.2 Taking care of the suppressor housing
    • 5.12.3 Servicing the suppressor
      • 5.12.3.1 Parts of the suppressor
      • 5.12.3.2 Regenerating the suppression rotor
      • 5.12.3.3 Cleaning the suppressor
      • 5.12.3.4 Replacing parts of the suppressor
  • 5.13 Peristaltic pump
    • 5.13.1 Notes on operating the peristaltic pump
    • 5.13.2 Servicing the peristaltic pump
      • 5.13.2.1 Replacing the pump tubing
      • 5.13.2.2 Replacing the filter
  • 5.14 Servicing the detector
  • 5.15 Rinsing the sample path
  • 5.16 Separation column
    • 5.16.1 Separating efficiency
    • 5.16.2 Protecting the separation column
    • 5.16.3 Storing the separation column
    • 5.16.4 Regenerating the separation column
  • 5.17 Quality Management and qualification with Metrohm
• 6 Troubleshooting
• 7 Technical specifications
  • 7.1 Reference conditions
  • 7.2 Device
  • 7.3 Ambient conditions
  • 7.4 Housing
  • 7.5 Leak sensor
  • 7.6 Column thermostat
  • 7.7 Eluent degasser
  • 7.8 High-pressure pump
  • 7.9 Injection valve
  • 7.10 Suppressor
  • 7.11 Peristaltic pump
  • 7.12 Detector
  • 7.13 Sample degasser
  • 7.14 Power connection
  • 7.15 Interfaces
  • 7.16 Safety specification
  • 7.17 Electromagnetic compatibility (EMC)
• 8 Warranty (guarantee)
• 9 Accessories
• Index