Texas Instruments CC2533 - Manual (Page 23)

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Figure 18: Using the EEPROM burner software
After successful programming, unplug the mini-USB cable, mount the CC2533EM on the
target module and plug in the mini-USB cable again. The target module will now appear as a
COM port in the device manager.
Remove the short on the pins 1(GND) and pin 11(I2C SDA) on the
interface header before clicking “Program EEPROM”