Introduction to the ibox anesthesia system – UVP iBox Anesthesia System User Manual

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iBox Anesthesia System

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Introduction to the iBox Anesthesia System

The iBox Anesthesia System is designed for the anesthesia of small animals. The system is a small
portable unit that has been designed for maximum efficiency, ease of use and low anesthetic gas
consumption.

The system delivers a precisely blended mixture of oxygen and isoflurane or sevoflurane into a
plastic induction chamber, offering ultra-efficient anesthetizing of animals. The chamber attaches to
a charcoal filter canister that releases safe, filtered air into the room.

After initial anesthetizing in the host cage, the animal can be moved to the breathing
device/manifold attached to the warming plate inside the iBox Imaging System. The non-
rebreathing gas delivery masks, or “nosecones,” are specifically designed for small animals. The
system allows safe controlled anesthesia during imaging procedures to keep the animal free of
movement.

Note that two styles of anesthesia kits are offered for use with UVP’s iBox Imaging System line: the
five-port and the single-port breathing device/manifold. The five-port kit is designed for use with the
iBox Scientia™ and iBox Spectra™ Small Animal Imaging Systems, while the single-port kit is
designed for the iBox Explorer™ Imaging Microscope. Most of the components are the same
between the two anesthesia kits, except for a few notable differences:

1. The five-port is able to accommodate up to five mice simultaneously, while the single-port

accommodates a single mouse.

2. The warming plate for the five-port kit is removable from the darkroom along with the

nosecone manifold, while the single-port’s warming plate is a slide-out unit attached to the
inside of the darkroom. Thus, only the single-port nosecone manifold and bracket are
removable from the darkroom.

NOTE: Anesthesia kits are designed to support the use of either isoflurane or sevoflurane agents
for anesthetization. Note that each kit is designed to accommodate either isoflurane or
sevoflurane, not both
. DO NOT use one agent in a system designed for the other, as permanent
system damage will occur. Read the label on the system to determine which type of agent it is
designed to utilize.



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