Canon PIXMA MP250 - Manual (Page 227)

4. Complete the setup
Click OK on the Page Setup tab.
When you execute print, the data is printed with the specified staple side and margin width.
Important
Staple Side and Specify Margin... appear grayed out and are unavailable when:
Borderless, Poster, or Booklet is selected for Page Layout.
Scaled is selected for Page Layout (When Duplex Printing is also selected, only Staple Side is
selectable).
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Page 227 of 678 pages Setting the Stapling Margin