Adobe InDesign - Manual (Page 225)

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2. If column guides are locked, choose View > Grids & Guides > Lock Column Guides to deselect it.
3. Using the Selection tool , drag a column guide. You can’t drag it past an adjacent column guide or beyond the edge of the page.
Dragging a column guide to create unequal column widths
To create columns with unequal gutters, create evenly spaced ruler guides and then drag individual guides to the desired location. (See Create
ruler guides.)
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