IntraServer Technology ITIpci 5100G/GF - Manual (Page 43)

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Changes to the optional configuration parameters (Jumbo Frame, or Dual
Homing) do not take effect until you reboot the system. If you will be making
changes to the other optional parameters during your configuration session,
you should wait to reboot until those changes are complete.
Note: If you modify parameters and put the system into service before
rebooting, you may experience configuration problems.
Perform this command to reboot the system:
# reboot -- -r