To setup a method to use the multimode source – Agilent Technologies G1978B User Manual

Page 36

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36

Multimode Source for 6100 Series Single Quad LC/MS Set-Up Guide

3

Methods

To setup a method to use the multimode source

To setup a method to use the multimode source

To have your method use a multimode source, follow these steps:

1 Open the MSD Spray Chamber dialog box by clicking Instrument > MSD

Spray Chamber in the Method and Run Control view.

2 Set Method Spray Chamber to MM-ES+APCI.

3 Verify that Installed Spray Chamber is set to MM-ES+APCI.

4 Make any other changes that are necessary for your method.

5 Click the OK button.

6 Open The Set up MSD Signals dialog box by clicking Instrument > More >

Set up MSD Signals in the Method and Run Control view.

7 Choose the desired ionization mode from the Ionization list. This list is

only visible if the Method Spray Chamber was set to MM-ES+APCI. You
may set the ionization mode to one of the following:

MM-ES

MM-APCI

MM-ES+APCI

8 Make any other changes that are necessary for your method.

9 Click the OK button.

WA R N I N G

The 6100 Series Single Quad LC/MS Liquid Chromatograph diverter valve is an
integral part of the G1978B safety system. The LC mobile phase flow must always be
connected to the diverter valve inlet filter. Never bypass the diverter valve and
connect directly to the nebulizer. If the diverter valve is used in a manner not
specified by Agilent Technologies, the protections provided by the diverter valve may
be impaired and the system may catch fire.

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