Epson Perfection V500 - Manual (Page 229)

Click Uninstall/Change, then click Continue in the User Account Control
window (Windows Vista), or click Change/Remove (Windows XP and 2000).
If a confirmation window appears, click OK.
Repeat steps 3 through 5 for each of the following programs.
Epson Event Manager
EPSON Perfection V500 Office Scanner Driver Update
Epson Scan PDF EXtensions
In some cases, a message may appear to prompt you to restart the computer.
If so, make sure I want to restart my computer now is selected and click
Finish.
Uninstalling Other Epson Software for Mac OS X
Note:
To uninstall applications, you must log on to a Computer Administrator
account. You cannot uninstall programs if you log on as a Limited
account user.
Quit all running applications.
Insert the scanner software CD-ROM into your Macintosh.
Open the Epson CD-ROM desktop icon, if necessary.
Double-click the Common folder, then double-click the Copy Utility folder.
Note:
You may have to scroll down to see these folders.
Double-click the Uninstaller icon.
In the Common folder, double-click the Event Manager folder.