Epson Perfection V500 - Manual (Page 72)

You can move the marquee, adjust its size, and create multiple marquees on one image (normal
preview only) to scan different image areas in separate scan files. Follow these steps.
To draw a marquee, move your cursor over a preview image. The pointer becomes a set of
cross-hairs.
Position the pointer in the area where you want to place the corner of your marquee and
click. Hold down the mouse button and drag the cross-hairs over the image to the opposite
corner of the desired scan area. Then release the mouse button. You see the moving
dotted line of the marquee.
Do one of the following to adjust the marquee.
To move the marquee, position your cursor inside the marquee. The pointer
becomes a hand. Click and drag the marquee to the desired location.