U.s. fda – Siemens C56 User Manual

Page 102

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U.S. FDA

101

2. Researchers conducted a large

battery of laboratory tests to assess

the effects of exposure to mobile

phone RF on genetic material. These

included tests for several kinds of ab-

normalities, including mutations,

chromosomal aberrations, DNA

strand breaks, and structural chang-

es in the genetic material of blood

cells called lymphocytes. None of

the tests showed any effect of the RF

except for the micronucleus assay,

which detects structural effects on

the genetic material. The cells in this

assay showed changes after expo-

sure to simulated cell phone radia-

tion, but only after 24 hours of expo-

sure. It is possible that exposing the

test cells to radiation for this long re-

sulted in heating. Since this assay is

known to be sensitive to heating,

heat alone could have caused the ab-

normalities to occur. The data al-

ready in the literature on the re-

sponse of the micronucleus assay to

RF are conflicting. Thus follow-up re-

search is necessary.

2

FDA is currently working with gov-

ernment, industry, and academic

groups to ensure the proper follow-

up to these industry-funded research

findings. Collaboration with the Cel-

lular Telecommunications Industry

Association (CTIA) in particular is ex-

pected to lead to FDA providing re-

search recommendations and scien-

tific oversight of new CTIA-funded

research based on such recommen-

dations.

Two other studies of interest have

been reported recently in the litera-

ture:
• Two groups of 18 people were ex-

posed to simulated mobile phone

signals under laboratory condi-

tions while they performed cogni-

tive function tests. There were no

changes in the subjects' ability to

recall words, numbers, or pic-

tures, or in their spatial memory,

but they were able to make choic-

es more quickly in one visual test

when they were exposed to simu-

lated mobile phone signals. This

was the only change noted among

more than 20 variables com-

pared.

3

• In a study of 209 brain tumor cas-

es and 425 matched controls,

there was no increased risk of

brain tumors associated with mo-

bile phone use. When tumors did

exist in certain locations, howev-

er, they were more likely to be on

the side of the head where the

mobile phone was used. Because

this occurred in only a small num-

ber of cases, the increased likeli-

hood was too small to be

statistically significant.

4

In summary, we do not have enough

information at this point to assure

the public that there are, or are not,

any low incident health problems as-

sociated with use of mobile phones.

FDA continues to work with all par-

ties, including other federal agencies

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