4 mode of operation for dialysis, Mode of operation for dialysis, Figure 4 – Metrohm Inline Dialysis User Manual

Page 11: Stopped-flow dialysis

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2 Overview

IC equipment: Dialysis

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5

2.4

Mode of operation for dialysis

Figure 4

Stopped-flow dialysis

Sample is delivered continuously on the sample side of the dialysis cell.
After a rinsing phase, the acceptor flow is stopped. Because of the con-
centration gradient, the ions pass through the membrane. The acceptor
flow remains stationary until a concentration equilibrium is achieved
between the two cell halves. The concentration in the acceptor solution
thus matches the concentration of the original sample. Afterwards, the
acceptor solution is injected directly into the ion chromatograph.

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