Chemical carcinogen use with carbon filters – Labconco Precise HEPA-Filtered Glove Boxes 5220231 User Manual

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Chapter 5: Using Your Glove Box

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Chemicals must be designated by NIOSH guidelines as acceptable for use
with chemical cartridge-type respirators (the exception is formaldehyde and
ammonia/amines, which use impregnated carbon). Chemicals not listed by
NIOSH in the Pocket Guide must be approved by Labconco Product
Specialist (or Engineering).

Inlet concentration must never exceed the IDLH (Immediately Dangerous to
Life and Health) concentrations.

Chemicals having a recommendation by NIOSH of at least “Escape
GMFOV” (Gas Mask Full-Face Respirator).

When evaporating a mixture of chemicals, the chemical having the lowest
TWA will be used to determine if the mixture meets the guidelines.

Call a Labconco Product Specialist at 1-800-821-5525 for assistance in
chemical appropriateness.

Hazardous Misapplications for Carbon Filters
with Volatile Chemicals

There is one scenario where the accessory FilterMate carbon filter
misapplication would be a part of a hazardous condition. If the user
continues to operate the glove box with FilterMate Portable Exhauster with
any of the following conditions, a potentially hazardous condition will exist:

1. The inlet concentration of vapors is greater than the TWA.
2. The carbon filter becomes saturated.
3. The ventilation of the room is insufficient to dilute the exhaust of the

enclosure to below the TWA for the chemical.


When the inlet concentration is greater than the TWA, extra measures must
be taken to monitor the filter and number of room air exchanges.

Chemical Carcinogen Use with Carbon Filters

Selected carcinogens may be used safely with accessory FilterMate carbon
filters under the following restrictions.

The use of a ventilated glove box with ducting to the
outside is always the preferred method when working with
carcinogens. The carbon filters should only be used, as a
last resort, when venting to the outside is not an option.

The potential carcinogens are listed in the NIOSH Pocket Guide to Chemical
Hazards as “Ca.” Each potential carcinogen must have a TWA of 1 or
greater; have minimum respirator recommendation of Escape GMFOV, and
an odor threshold significantly lower than the TWA for the chemical.

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