Infection, Infection 28 – ZOLL Thermogard XP IVTM Physician Manual User Manual

Page 29

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ZOLL IVTM™ System

Physicians' Manual

600248-001 Rev 3

28

Infection

Catheter Related Bloodstream Infection (CR-BSI) are of concern with any catheter.
There is a significantly increased risk of CR-BSI [42] associated with:

• Inexperience of the operator and nurse-to-patient ratio in the intensive

care unit,

• Catheter insertion with less than maximal sterile barriers,
• Placement of a CVC in the internal jugular or femoral vein rather than

subclavian vein,

• Placement in an old site by guidewire exchange,
• Heavy colonization of the insertion site or contamination of a catheter

hub, and

• Duration of CVC placement > 7 days.

The US Center for Diseases Control has published Guidelines for the Prevention of
Intravascular Catheter-Related Infections[43]. The recommended preventive
strategies with the strongest supportive evidence are:

• Education and training of healthcare providers who insert and maintain

catheters;

• Maximal sterile barrier precautions during central venous catheter

insertion;

• Use of a 2% chlorhexidine preparation for skin antisepsis;
• No routine replacement of central venous catheters for prevention of

infection; and

• Use of antiseptic/antibiotic-impregnated short-term central venous

catheters if the rate of infection is high despite adherence to other
strategies (ie, education and training, maximal sterile barrier precautions,
and 2% chlorhexidine for skin antisepsis).

The same Guidelines make the following recommendations relating to the
replacement of catheters in relation to the management of catheter-related infection.

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