BUCHI Syncor Polyvap - Manual (Page 38)

Syncore ® Accessories
36 version E
Temperature of the cooling medium
The ideal choice of the coolant temperature is depending
on the boling point of the solvent, the reagents, and the set
temperature on the rack heater.
Wrong (too high) temperature of the reflux module/flushback
module or the cooling medium can lead to loss of solvent or
volatile reagents through the inert gas flow. Flow of cooling
medium through the reflux module/flushback module and
the temperature of the cooling medium are to be controlled
before reactions are carried out.
Solvents or reagents, heated above the boiling point,
must be kept in constant motion. Stopping the shaking
motion can lead to boiling retardation and loss of reaction
mixture.
Guidelines for the operation of the reflux module/flushback
module are contained in the following table:
Boiling point range
of the solvent at
normal pressure
Rack heating
Temperatur of the
cooling medium of
the reflux/flushback
module
35 - 60°C Maximal 5°C above the boiling point of the lowest boiling
point solvent/reagent max. 0°C
60 - 100°C Maximal 10°C above the boiling point of the lowest boiling
point solvent/reagent max. 10°C
100 - 150°C Maximal 20°C above the boiling point of the lowest boiling
point solvent/reagent max. 15°C
Less than 35°C - No efficient return flow
35 - 60°C > 5°C above the lowest boiling point of solvent/reagent No efficient return flow
60 - 100°C > 10°C above the lowest boiling point of solvent/reagent No efficient return flow
Table 2: Selection of the cooling medium temperature
Function,putting into operation, operation and maintenace