Multichannel Systems MEA1060-Up-BC Manual User Manual

Page 42

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MEA Amplifier with Blanking Circuit for Upright Microscopes

42

Voltage driven stimulation (1 V, electrode 33) on 100 μm gold electrodes.

You see only small artifacts on the channels 21 and 22 with tracks next to the stimulation
electrode 33. The blanking performance when using the silver pellet as a ground was
reproducible. However, with the internal reference electrode, there could sometimes
be observed an artifact with very slow kinetics. If you observe such problems, please
try out a silver pellet for grounding the bath.

Standard 60MEA200/30iR-Ti

This example shows data from a syncytium of cardiac cells treated with a biphasic 2 V bipolar
stimulus pulse field applied to electrodes No 36 and No 46. Please see the schema below.

The blanking artefact is in the range of 10 μV that is a negligible value in comparison to
the amplitude of the cardiac field potentials ranging from a few hundred μV to several mV.
You see the stimulation artefacts on all electrode channels.

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