3first use of the mea amplifier, 1 welcome to the mea amplifier – Multichannel Systems MEA1060-Up-BC Manual User Manual

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First Use of the MEA Amplifier

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3

First Use of the MEA Amplifier

3.1 Welcome to the MEA Amplifier

Raw data from up to 60 electrodes of a microelectrode array (MEA) is amplified by 60 channels
of pre- and filter amplifiers.

The MEA sensor is placed directly into the small-sized MEA preamplifier with blanking circuit
(MEA1060-BC-PA). When the amplifier is closed, the contact pins in the lid of the amplifier are
pressed onto the MEA contact pads. The very close location of the amplifier to the MEA sensor
is very favorable concerning a high signal-to-noise ratio.

MEA amplifiers can be ordered with different gain and bandwidth configurations by the user's
choice. For example, typical pass bands would be 1 to 300 Hz for recording field potentials and
300 to 3000 Hz for recording action potentials. It is also possible to use a broadband amplifier and
filter the data with the digital filter of the free MC_Rack program. Gain settings from 100 to 5000
are possible.

The amplifier is connected to the data acquisition computer via a single 68-pin MCS standard
cable. The analog output signals of the MEA amplifier are then acquired and digitized by the
MC_Card (MEA-System) or your custom data acquisition system.

MEA amplifiers have an integrated heating system for controlling the MEA's temperature.
The desired temperature can be easily programmed with a temperature controller. You will not
need an incubator during recording all environmental conditions are reliably controlled directly
in the MEA dish.

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