Integra LifeSciences Sutures, Plain and Chromic Gut, Absorbable - Manual (Page 2)

Acceptable surgical practice should be followed with respect to drainage and closure of contaminated or infected
wounds.
The use of supplemental nonabsorbable sutures should be considered by the surgeon in the closure of sites, which
may undergo expansion, stretching, or distention or which may require additional support.
Certain patients may be hypersensitive to collagen or chromium and might exhibit an immunological reaction
resulting in inflammation, tissue granulation or fibrosis, wound suppuration and bleeding, as well as sinus
formation.
Precautions
In handling this or any other suture material, care should be taken to avoid damage from handling. Avoid crushing
or crimping damage due to application of surgical instruments such as forceps or needle holders.
Adequate knot security requires the accepted surgical technique of flat, square ties, with additional throws as
warranted by surgical circumstance and the experience of the surgeon. The use of additional throws may be
particularly appropriate when knotting monofilaments.
The surgeon should avoid unnecessary tension when running down knots, to reduce the occurrence of surface
fraying and weakening of the stand.
Under some circumstances, notably orthopedic procedures, immobilization by external support may be employed at
the discretion of the surgeon.
Adverse Reactions
Adverse effects associated with the use of this device include: wound dehiscence, variable rates of absorption
over time (depending on the type of suture used, the presence of infection and the tissue site), failure to provide
adequate wound support in closure of sites where expansion, stretching or distension occur, etc., unless additional
support is supplied through the use of nonabsorbable suture material failure to provide adequate wound support
in elderly, malnourished or debilitated patients or in patients suffering from cancer, anemia, obesity, diabetes,
infection or other conditions which may delay wound healing, allergic response in patients with known sensitivities
to collagen or chromium which may result in an immunological reaction resulting in inflammation, tissue
granulation or fibrosis, wound suppuration and bleeding, as well as sinus formation, infected wounds, moderate
tissue inflammatory response characteristic of foreign body response, calculi formation in urinary and biliary tracts
when prolonged contact with salt solutions such as urine and bide occurs, and transitory local irritation
How Supplied
Plain and Chromic Gut Sutures are available sterile, in U.S.P. sizes 3-0 through 5-0 (metric sizes 1.0 - 6.0) in chromic
and plain gut, in a variety of lengths, with permanently attached needles. These sutures are available in one dozen
boxes.
CAutIon
Federal (USA) law restricts this device to sale by or on the order of a dentist or physician.
Manufactured for:
Miltex, Inc.
589 Davies Drive
York, PA 17402 USA
800-645-8000
www.miltex.com
Copyright © 2010 Integra LifeSciences Corporation