Multichannel Systems HiClamp Manual - Manual (Page 18)

HiClamp Manual
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3.4 Mechanical Functionality of the HiClamp
The specific characteristic of the mechanical components of the HiClamp device is their mobility
in three dimensions. The movement of the table complex in dependency of the movement and
adjustment of the measuring complex is the main idea of the HiClamp’s functionality.
The table complex moves on track rails in X, Y and Z direction under software control of very
precise motors.
The basket with the oocyte inside moves in Y direction only, but is not moving during recording
minimizing recording artifacts and oocyte damage during transport.
The HiClamp is based on a innovative system in which the cell (or preparation) is exposed to
a test solution by moving it physically into the solution of interest, whereas in a standard system
the solution is applied on the cell. The provided solutions are disposed in a 96 well plate which
is fixed on the left part of the table. The cell (or preparation) is carried in the basket in the center
of the HiClamp. After adjustment of table complex and measuring head, the basket keeps
stationary while the table moves to immerge the cell in the desired solution.