Multichannel Systems LTP-Director Manual - Manual (Page 54)

LTP-Director Manual
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LTP / LTD Induction
Click the "LTP / LTD Induction" icon. This icon is available in three versions. The number on
the pulse train symbol indicates, which stimulation pathway is used for the LTP / LTD Induction.
1 means stimulation pathway S1, 2 means stimulation pathway S2, and 1+2 means both
stimulation pathways.
The LTP / LTD Induction phase defines the high or low frequency stimulation that induces
either long term potentiation LTP or long term depression LTD.
"Pathways": The stimulus can be delivered on stimulation pathway S1, or on S2, or on
both stimulation pathways. Usually, LTP or LTD is induced just on one of the both pathways,
and the other one is used as an internal control. LTP can be induced either by a high frequency
stimulation or by a theta burst. LTD is induced by low frequency stimulation. You are free to
change the stimulation pathway for each LTP / LTD Induction phase of the experiment.
Three different "LTP / LTD Induction" protocols can be selected:
"HFS" (high frequency stimulation): A pulse with stimuli in equal time intervals is applied.
The pulse duration "Train Duration" in ms, and the frequency "Freq." in Hz can be selected.
"Theta Burst" (high frequency pulse trains): An adjustable number of pulse trains is applied.
The trains have an inter train interval of 200 ms. There are four pulses each train with the
high frequency of 100 Hz per train.