Epson 4500 - Manual (Page 52)

Using Single Sheets
2. Turn on
the printer. (The green POWER light should come on.)
Note:
Do not insert paper in the printer before turning on the
printer.
3.
Move the left edge guide so that it locks in place next to the guide
mark. (You may want to change this position later, depending on
the margin settings of your application program.)
2-4
Paper Handling