4
Instructions for use V1.3 RevB – 09/2012
2.
Table of contents
1.
Important information .................................................................................................................................................... 3
Table of contents ............................................................................................................................................................ 4
3.
Safety instructions for handling the instrument ........................................................................................................ 5
3.1
Safety features ............................................................................................................................................................................................ 5
3.1.1
Locking the handwheel .............................................................................................................................................................................. 5
3.1.2
Knife guard ................................................................................................................................................................................................... 5
3.2
General hazards .......................................................................................................................................................................................... 5
4.
Technical data ................................................................................................................................................................ 8
5.
General description ....................................................................................................................................................... 9
5.1
Leica CM 1100 Overview ............................................................................................................................................................................ 9
5.2
Product description .................................................................................................................................................................................. 10
5.3
Standard delivery range ........................................................................................................................................................................... 10
6.
Unpacking and installation .................................................................................................................................... 11
6.1
Unpacking ................................................................................................................................................................................................... 11
6.2
Site requirements ..................................................................................................................................................................................... 12
6.3
Transport to the installation site ............................................................................................................................................................. 12
7.
First use of the instrument ....................................................................................................................................... 13
7.1
Connection to mains power .................................................................................................................................................................... 13
7.2
Installing the accessories ........................................................................................................................................................................ 13
7.3
Switching on .............................................................................................................................................................................................. 14
7.4
Functions of the control unit ................................................................................................................................................................... 14
7.4.1
LEDs ............................................................................................................................................................................................................. 14
7.4.2
Function keys ............................................................................................................................................................................................. 14
7.4.3
Setting user definable parameters ........................................................................................................................................................ 15
7.4.4
Starting and terminating a manual defrost cycle ............................................................................................................................... 15
7.5
Temperature selection chart (in minus °C) .......................................................................................................................................... 16
8.
Daily operation ........................................................................................................................................................... 17
8.1
Specimen discs ......................................................................................................................................................................................... 17
8.1.1
Specimen freezing .................................................................................................................................................................................... 17
8.1.2
Fixing the specimen disc in the specimen head ................................................................................................................................. 17
8.2
Knife holder CE .......................................................................................................................................................................................... 18
8.2.1
Changing the rear pressure plate .......................................................................................................................................................... 18
8.2.2
Adjusting the rear pressure plate .......................................................................................................................................................... 18
8.2.3
Adjusting the front pressure plate .......................................................................................................................................................... 19
8.2.4
Inserting the blade .................................................................................................................................................................................... 19
8.2.5
Lateral displacement ................................................................................................................................................................................ 20
8.2.6
Adjusting the anti-roll plate ..................................................................................................................................................................... 20
8.2.7
Replacing the glass anti-roll plate ......................................................................................................................................................... 21
8.3
Coarse feed wheel .................................................................................................................................................................................... 22
8.4
Trimming .................................................................................................................................................................................................... 22
8.5
Sectioning .................................................................................................................................................................................................. 23
8.6
Section transfer ......................................................................................................................................................................................... 23
8.7
Defrosting ................................................................................................................................................................................................... 24
8.7.1
Programming an automatic defrost cycle ............................................................................................................................................ 24
8.7.2
Starting a manual defrost cycle ............................................................................................................................................................. 24
9.
Trouble sh ooting ....................................................................................................................................................... 25
10.
Cleaning and disinfection ....................................................................................................................................... 28
10.1
Cleaning ...................................................................................................................................................................................................... 28
10.2
Spray disinfection with Leica Cryofect ................................................................................................................................................. 28
10.3
Removal of the microtome ...................................................................................................................................................................... 29
10.4
Reassembly of the microtome ................................................................................................................................................................ 30
11.
Maintenance ............................................................................................................................................................... 31
11.1
General maintenance ............................................................................................................................................................................... 31
11.2
Fuse replacement ..................................................................................................................................................................................... 31
12.
Optional accessories ............................................................................................................................................... 32
12.1
Mobile heat extractor ............................................................................................................................................................................... 32
12.2
Thermal block ............................................................................................................................................................................................ 32
13.
Warranty and service ............................................................................................................................................... 33
14.
Decontamination Certificate
(master)
...................................................................................................................... 34
16.
Information for the People´s Republic of China ................................................................................................ 35
