Ratoc Systems U2SCXU - Manual (Page 58)

Macintosh
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5)After you have done settings, click [Write]. The message saying updating
completed will appear. Click [OK]. Select [Quit] from the [File] menu.
Remove the U2SCXU from the Mac and turn off the SCSI device attached
to the U2SCXU.
6)Change the settings from [U2SCX Configuration] to the previous setting
with [Extensions Manager] and restart your Mac. Turn on the SCSI device
and connect the U2SCXU to the Mac. Your settings now starts working.