2 hardware – Multichannel Systems HiClamp Manual User Manual
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HiClamp
9
3.2 Hardware
The HiClamp hardware
The HiClamp is compatible with standard lab equipment and can be easily integrated in your
working environment. Software controls replace any knobs on the device. The HiClamp is
straightforward and easy to operate; handling does not require special skills or special equipment.
Recording and cultivation of Xenopus oocytes is performed using disposable standard 96 well
plates, which are commercially available from several providers. The oocytes are plated into the
wells in a couple of minutes and can be kept for several days. The oocytes do not have to leave
the plate anymore; you can easily transfer the oocytes from the incubator to the HiClamp and
back again.
A quick alignment process under camera control guarantees that the glass microelectrodes
in the measuring head impale the oocyte precisely centered before recording.
The ClampAmpC is a specifically designed digital TEVC amplifier and is completely automated.
The Syringe System arranges the aspiration of the cell when loading it into the basket via low
pressure.
The Perfusion System with inlet and outlet tubes and external peristaltic pump is for managing
the wash and test station placed between the 96 well plates on the table.