Multichannel Systems Cardio2D Manual - Manual (Page 59)

Cardio 2D Software
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Click heartbeat "HB" tab in single channel view.
The HB tab shows a diagram of the duration of the RR interval in ms if you select "RRI (ms)"
from the drop down menu. In whole heart experiments the RR interval is defining one complete
heartbeat from one ventricular depolarization to the next ventricular depolarization. 1/RR is the
beating frequency of the heart. Any modulation of the beating frequency is an indicator for
possible arrhythmia. So arrhythmia or proarhythmic events can be detected. In cell cultures ECG
terminology does not apply. However the depolarization driven by rapid sodium channels causes
an as distinctive peak as the QRS complex in the ECG. Analysis can be performed in strict analogy
to the ECG analysis in respect of signal propagation patterns and conduction velocity.
If you select "Heart Rate (Hz)", the rate of the heartbeats is calculated from the reciprocal value
of the RR interval. The last actual value of the RRI (ms) or of the heart rate (Hz) is displayed in red
above the plot.
Click the "Edit Plot" icon . A plot menu will open.
With the help of the plot menu it is possible to modify a lot of plot parameters. For example,
you can adapt the figure to a special layout wanted for a special publication. Please see also
chapter "General Software Features".