Multichannel Systems Cardio2D Manual - Manual (Page 111)

Cardio 2D+ Analyzer Software
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Enable the check box "On" to use the QT-related Analysis tool.
Select the "Detection Deadtime" in ms in the first up down box to define the time span in which
no detection is performed.
Detecting extremal values for QT-related Analysis is achieved by analysing the slope of the signal.
Select the "Slope Calculation" in ms in the second up down box to define the time interval in
which the slope of one point of the signal is calculated. Please read chapter "Automated
Waveform Detection" in "Analyzer Setting". This feature works like a filter, because the
remaining noise is reduced.
QT-related Interval
The left window shows the different recording phases of the selected electrode, starting with
the smallest amount of compound, which is the reference by default (0 μM). The molarity of
the compound and the number of detected and averaged heartbeats are displayed in the green
rectangle in the upper left edge. The blue bar indicates the end of the QT-like Interval, calculated
by the computer. If you change the level manually, the bar turns into red color. The duration time
of the QT-like Interval in milliseconds is written beside the bar.
Click onto the green or red rectangle to select a recording for the calculation of the dose response
curve.