Epson Epson - Manual (Page 142)

Follow these steps to remove a drive from the rear internal
bracket:
1. Remove the drive and power cable from the back of each
drive in the rear internal bracket.
2. If you are removing the only IDE drive connected to the
interface, you may want to disconnect the device cable from
the interface on the main system board and remove it from
the computer.
Installing and Removing Tower Drives 6-21