Martin Christ Epsilon 2-10D LSCplus - Manual (Page 85)

Freeze-dryer EPSILON 2-10D LSCplus
6 Operation
Version 04/2013, Rev. 1.5 of 16/12/2014 • sb
85
Translation of the original operating manual
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6.6 Optional extensions and special equipment
Aeration, stoppering, storage
see also chapter 6.5.3.1 - "Creating a program", Button ">>more"
This option is available only in combination with the PGMplus programmer
module and if the freeze-dryer is equipped with an automatic aeration valve
and a hydraulic shelf movement system. It offers automatic sealing of the
product vials with pre-inserted rubber stoppers under partial vacuum and
subsequent storage on the shelves under defined conditions as an integral
part of a freeze-drying program.
Pressure increase test
see also chapter 6.5.3.1 - "Creating a program", Button ">>more"
The pressure increase test can only be performed with the double-
chamber method. During the pressure increase test, the intermediate valve
prevents the flow of steam from the drying chamber to the ice condenser so
that the water vapour of the sublimation cannot flow off. The result is a
more or less distinct pressure increase that is measured in the product
chamber. The pressure increase test is used as a criterion for the automatic
switching from the main drying phase to the final drying phase as well as
for identifying the end of the process.
Gas injection with a proportional valve
see also chapter 6.5.1.3 - "Main window "Options"", section "General"
If the freeze-dryer is equipped with a proportional gas injection valve, the
method that is to be used for vacuum control can be preselected. The
method can be saved together with a recipe.
Inertisation
see also chapter 6.5.1.3 - "Main window "Options"", section "General"
If products with a high solvent concentration are dried in an oxygen
atmosphere, explosive mixtures may form. In order to dry these types of
products, the freeze-dryer is equipped with a door-controlled inertisation
system that uses nitrogen or another inert gas.
Comparative pressure measurement
see also chapter 6.5.3.1 - "Creating a program", Button ">>more"
During the sublimation, i.e. when the concentration of water vapour
molecules is rather high in the atmosphere, the value that is provided by
the gas-type-dependent vacuum sensor of the "Pirani" type (e.g. Thyracont
VSP62/63) in the drying chamber deviates from the value that is provided
by a capacitive vacuum sensor (e.g. MKS 722B). When the proportion of
water vapour molecules decreases towards the end of the main drying
phase, the two sensors fall increasingly in line with one another. This
difference will be evaluated and used as an indicator for identifying the
drying end of the main drying phase.