Document Outline

• Table of contents
• Table of figures
• 1 Introduction
  • 1.1 Instrument description
  • 1.2 Titration and measuring modes
  • 1.3 About the documentation
    • 1.3.1 Symbols and conventions
• 2 Safety instructions
  • 2.1 General notes on safety
  • 2.2 Electrical safety
  • 2.3 Tubing and capillary connections
  • 2.4 Flammable solvents and chemicals
  • 2.5 Recycling and disposal
• 3 Overview of the instrument
• 4 Installation
  • 4.1 Setting up the instrument
    • 4.1.1 Packaging
    • 4.1.2 Checks
    • 4.1.3 Location
• 5 Titrations
  • 5.1 Dynamic equivalence point titration (DET)
  • 5.2 Monotonic equivalence point titration (MET)
  • 5.3 Endpoint titration (SET)
  • 5.4 Water determination according to Karl Fischer (KFT)
  • 5.5 Endpoint titration with constant maintenance of the measured value (STAT)
• 6 Operation
  • 6.1 Switching the instrument on and off
  • 6.2 Fundamentals of operation
    • 6.2.1 Touch-sensitive screen
    • 6.2.2 Display elements and controls
    • 6.2.3 Status display
    • 6.2.4 Entering text and numbers
• 7 System settings
  • 7.1 General system settings
    • 7.1.1 Selecting the dialog language
    • 7.1.2 Setting the date, time and local time
  • 7.2 System-specific dialog options
  • 7.3 User administration
    • 7.3.1 Editing the user configuration
    • 7.3.2 Creating an identification profile
    • 7.3.3 Defining login options
    • 7.3.4 Password options
    • 7.3.5 Modification options
    • 7.3.6 Reasons
    • 7.3.7 Audit Trail
  • 7.4 Measured value display
  • 7.5 Acoustic signals
• 8 Titrants
  • 8.1 Adding a new titrant
  • 8.2 Editing titrant data
  • 8.3 Monitoring the working life
  • 8.4 Dosing unit
    • 8.4.1 Parameters for preparing (PREP) and emptying (EMPTY)
    • 8.4.2 Tubing parameters
    • 8.4.3 Shift direction of the valve disk
  • 8.5 Exchange unit
    • 8.5.1 Parameters for the preparation (PREP)
    • 8.5.2 Tubing parameters
  • 8.6 GLP test for exchange unit and dosing unit
  • 8.7 Titer determination options and data
    • 8.7.1 Titer validity
    • 8.7.2 Properties of the previous titer determinations
• 9 Reagents
  • 9.1 Editing reagent data
  • 9.2 Reagent monitoring
• 10 Sensors
  • 10.1 Adding a new sensor
  • 10.2 Editing the sensor data
  • 10.3 Monitoring the working life
  • 10.4 Calibration data (for pH- and ISE electrodes and conductivity measuring cells only)
    • 10.4.1 Properties of the previous calibrations
  • 10.5 Limit values for the calibration data
  • 10.6 Monitoring the calibration interval (only for pH and ion-selective electrodes and conductivity measuring cells)
• 11 Device manager
  • 11.1 Adding a new device
  • 11.2 Configuring the instrument
  • 11.3  Touch Control
    • 11.3.1 E-mail
    • 11.3.2 PC/LIMS report
    • 11.3.3 Shared memory
    • 11.3.4 TCP/IP settings
  • 11.4 Metrohm control devices
    • 11.4.1 Properties – Control device
    • 11.4.2 Properties – Measuring input
    • 11.4.3 Properties – MSB connector
    • 11.4.4 Properties – Peripheral devices
  • 11.5 USB Sample Processor
    • 11.5.1 Properties – Sample Processor
    • 11.5.2 Properties – Tower
    • 11.5.3 Properties – Swing Head
  • 11.6 Sample racks
    • 11.6.1 Editing rack data
    • 11.6.2 Rack adjustment
  • 11.7 Printer
    • 11.7.1 PDF settings
    • 11.7.2 Network printer
    • 11.7.3 More options
  • 11.8 Balance
  • 11.9 USB/RS-232 adapter
  • 11.10 PC keyboard
  • 11.11 Barcode reader
• 12 File manager
  • 12.1 Managing files
    • 12.1.1 Copying a file
    • 12.1.2 Renaming a file
    • 12.1.3 File properties
  • 12.2 External storage medium
  • 12.3 Creating backups / Restoring data
    • 12.3.1 Restoring data
• 13 GLP manager
  • 13.1 Automatic system test
  • 13.2 Test tools
  • 13.3 GLP tests for measurement and titration
    • 13.3.1 Parameter description
  • 13.4 System validation
    • 13.4.1 Parameter description
  • 13.5 System monitoring
    • 13.5.1 Service interval
    • 13.5.2 Backup interval
• 14 Common variables
  • 14.1 Editing common variables
  • 14.2 Properties of common variables
  • 14.3 Monitoring validity
  • 14.4 Assigning a result automatically to a common variable
• 15 Templates
  • 15.1 Sample data
    • 15.1.1 Sample identification list
    • 15.1.2 Sample assignment table
  • 15.2 Custom result templates
    • 15.2.1 Editing result templates
  • 15.3 Input lines
    • 15.3.1 Editing the input signal
  • 15.4 Output lines
    • 15.4.1 Editing the output signal
  • 15.5 Custom calibration buffers
    • 15.5.1 Defining calibration buffers
  • 15.6 Report header
  • 15.7 Custom electrode type
    • 15.7.1 Limit values for the electrode rating
• 16 Methods
  • 16.1 Creating a new method
  • 16.2 Saving a method
  • 16.3 Loading a method
  • 16.4 Editing a method
    • 16.4.1 Inserting a command
  • 16.5 Method options
    • 16.5.1 Start options
    • 16.5.2 Stop options
    • 16.5.3 Sample data
    • 16.5.4 Method properties
    • 16.5.5 Note
    • 16.5.6 Saving a determination automatically
• 17 Electronic signatures
  • 17.1 Signing methods/determinations electronically
  • 17.2 Deleting electronic signatures
• 18 Control
• 19 Favorites
  • 19.1 Creating favorites
    • 19.1.1 Editing favorites
• 20 Sample data
  • 20.1 Entering sample data in the main dialog
  • 20.2 Requesting sample data at the start of the determination
• 21 Sample table
  • 21.1 General
  • 21.2 Edit the sample data
  • 21.3 Properties
• 22 Determination run
  • 22.1 Carrying out a single determination
  • 22.2 Performing a sample series
  • 22.3 Canceling determinations manually
• 23 Live modifications
  • 23.1 Editing the sample data of the running determination
  • 23.2 Editing the sample table while a determination is running
  • 23.3 Live display
  • 23.4 Live parameters
• 24 Results and more determination data
  • 24.1 More determination data
    • 24.1.1 Details
  • 24.2 Messages
  • 24.3 Local common variables
  • 24.4 Determination properties
  • 24.5 Loading a determination
    • 24.5.1 Determination list
  • 24.6 Saving a determination
  • 24.7 Curves
  • 24.8 Recalculation and reevaluation
• 25 Statistics
  • 25.1 Displaying details for a result
  • 25.2 Deleting statistical data
  • 25.3 Adding a determination to a determination series
• 26 Result table
  • 26.1 Properties
  • 26.2 Saving the result table
  • 26.3 Loading the result table
• 27 Printing
  • 27.1 General report options
  • 27.2 Settings of the individual reports
  • 27.3 List of all printable reports
• 28 Manual control
  • 28.1 Opening and closing the manual control
  • 28.2 Measuring
    • 28.2.1 Parameter description
  • 28.3 Dosing
    • 28.3.1 Continuous dosing
    • 28.3.2 Dosing fixed volumes
    • 28.3.3 Preparing
    • 28.3.4 Emptying
    • 28.3.5 Filling
    • 28.3.6 Replacing reagent
  • 28.4 Stirring
  • 28.5 Conditioning a titration cell
    • 28.5.1 Parameter description
  • 28.6 Remote
  • 28.7 USB Sample Processor
    • 28.7.1 Moving the lift
    • 28.7.2 Moving to a rack position
    • 28.7.3 External positions
• 29 Parameters
  • 29.1 Dynamic equivalence point titrations (DET)
    • 29.1.1 Start conditions
    • 29.1.2 Titration parameters
    • 29.1.3 Stop conditions
    • 29.1.4 Potentiometric evaluation
    • 29.1.5 Control device
    • 29.1.6 Sensor
    • 29.1.7 Dosing device
    • 29.1.8 Stirrer
  • 29.2 Monotonic equivalence point titrations (MET)
    • 29.2.1 Start conditions
    • 29.2.2 Titration parameters
    • 29.2.3 Stop conditions
    • 29.2.4 Potentiometric evaluation
    • 29.2.5 Control device
    • 29.2.6 Sensor
    • 29.2.7 Dosing device
    • 29.2.8 Stirrer
  • 29.3 Endpoint titrations (SET)
    • 29.3.1 Start conditions
    • 29.3.2 Control parameters
    • 29.3.3 Titration parameters
    • 29.3.4 Stop conditions
    • 29.3.5 Conditioning
    • 29.3.6 Cell
    • 29.3.7 Control device
    • 29.3.8 Sensor
    • 29.3.9 Dosing device
    • 29.3.10 Stirrer
  • 29.4 Volumetric Karl Fischer titrations (KFT)
    • 29.4.1 Start conditions
    • 29.4.2 Control parameters
    • 29.4.3 Titration parameters
    • 29.4.4 Stop conditions
    • 29.4.5 Conditioning
    • 29.4.6 Cell
    • 29.4.7 Control device
    • 29.4.8 Sensor
    • 29.4.9 Dosing device
    • 29.4.10 Stirrer
  • 29.5 Coulometric Karl Fischer titrations (KFC)
    • 29.5.1 Control parameters
    • 29.5.2 Titration parameters
    • 29.5.3 Stop conditions
    • 29.5.4 Conditioning
    • 29.5.5 Cell
    • 29.5.6 Control device
    • 29.5.7 Sensor
    • 29.5.8 Stirrer
  • 29.6 Bromine index determination (BRC)
    • 29.6.1 Control parameters
    • 29.6.2 Titration parameters
    • 29.6.3 Stop conditions
    • 29.6.4 Conditioning
    • 29.6.5 Cell
    • 29.6.6 Control device
    • 29.6.7 Sensor
    • 29.6.8 Stirrer
  • 29.7 STAT titrations (STAT)
    • 29.7.1 Start conditions
    • 29.7.2 Control parameters
    • 29.7.3 Titration parameters
    • 29.7.4 Stop conditions
    • 29.7.5 Monitoring
    • 29.7.6 Control device
    • 29.7.7 Sensor
    • 29.7.8 Dosing device
    • 29.7.9 Stirrer
  • 29.8 Manual titrations (MAT)
    • 29.8.1 Dosing parameters
    • 29.8.2 Control device
    • 29.8.3 Sensor
    • 29.8.4 Dosing device
    • 29.8.5 Stirrer
  • 29.9 Measurements (MEAS)
    • 29.9.1 Measuring parameters
    • 29.9.2 Standard addition
    • 29.9.3 Control device
    • 29.9.4 Sensor
    • 29.9.5 Stirrer
  • 29.10 Calibration of sensors (CAL)
    • 29.10.1 Calibration parameters (CAL pH)
    • 29.10.2 Calibration parameters (CAL Conc)
    • 29.10.3 Calibration parameters (CAL Cond)
    • 29.10.4 Control device
    • 29.10.5 Sensor
    • 29.10.6 Stirrer
  • 29.11 Electrode test for pH electrodes (ELT)
    • 29.11.1 Electrode test parameters
    • 29.11.2 Control device
    • 29.11.3 Sensor
    • 29.11.4 Stirrer
    • 29.11.5 Further information
  • 29.12 Evaluations (EVAL)
    • 29.12.1 Fixed endpoint evaluation (EVAL FIX-EP)
    • 29.12.2 pK value and half neutralization potential evaluation (EVAL pK/HNP)
    • 29.12.3 Minimum and maximum evaluation (EVAL MIN/MAX)
    • 29.12.4 Break point evaluation (EVAL BREAK)
    • 29.12.5 Rate evaluation (EVAL RATE)
  • 29.13 Calculations
    • 29.13.1 Calculations (CALC)
      • 29.13.1.1 Loading a result template
      • 29.13.1.2 Editing a calculation
    • 29.13.2 Calculations (CALC LIVE)
    • 29.13.3 Formula editor
      • 29.13.3.1 Variables
      • 29.13.3.2 Mathematical functions
      • 29.13.3.3 Variable list
  • 29.14 Reports (REPORT)
    • 29.14.1 General report options
    • 29.14.2 Settings of the individual reports
    • 29.14.3 List of reports
  • 29.15 Dosing and Liquid Handling
    • 29.15.1 Preparing an exchange or dosing unit (PREP)
    • 29.15.2 Emptying a dosing unit (EMPTY)
    • 29.15.3 Dosing a specified volume (ADD)
      • 29.15.3.1 Dosing parameters
      • 29.15.3.2 Control device
      • 29.15.3.3 Dosing device
      • 29.15.3.4 Stirrer
    • 29.15.4 Liquid Handling (LQH)
      • 29.15.4.1 Liquid Handling parameters
      • 29.15.4.2 Control device
      • 29.15.4.3 Dosing device
    • 29.15.5 Monitored dosing (DOS)
      • 29.15.5.1 Dosing parameters
      • 29.15.5.2 Stop conditions
      • 29.15.5.3 Monitoring
      • 29.15.5.4 Control device
      • 29.15.5.5 Sensor
      • 29.15.5.6 Dosing device
      • 29.15.5.7 Stirrer
  • 29.16 Communication
    • 29.16.1 Scanning remote lines (SCAN)
    • 29.16.2 Setting remote lines (CTRL)
    • 29.16.3 Scanning the RS-232 interface (SCAN RS)
    • 29.16.4 Defining RS-232 commands (CONTROL RS)
  • 29.17 Automation
    • 29.17.1 Rotating sample rack (MOVE)
    • 29.17.2 Moving the lift (LIFT)
    • 29.17.3 Controlling pumps (PUMP)
    • 29.17.4 Resetting the rack (RACK)
    • 29.17.5 Defining the sample variable (SAMPLE)
    • 29.17.6 Creating a subsequence (SUBSEQ)
      • 29.17.6.1 Loading / saving a subsequence
      • 29.17.6.2 Subsequence options
  • 29.18 Miscellaneous commands
    • 29.18.1 Controlling a stirrer (STIR)
    • 29.18.2 Pausing the method run (WAIT)
    • 29.18.3 Scan data (REQUEST)
    • 29.18.4 Defining an acoustic signal (BEEP)
    • 29.18.5 Signing a determination (SIGN)
    • 29.18.6 Canceling the method run (END)
• 30 Operation and maintenance
  • 30.1 System initialization
  • 30.2 Quality management and qualification with Metrohm
• 31 Troubleshooting
  • 31.1 Editing methods
  • 31.2 Sample table
  • 31.3 Results/Statistics
  • 31.4 Printing
  • 31.5 Manual control
  • 31.6 Miscellaneous
  • 31.7 SET titration
  • 31.8 Karl Fischer titration
  • 31.9 STAT titration
• 32 Appendix
  • 32.1 Dosing unit
    • 32.1.1 Maximum dosing and filling rate
    • 32.1.2 Default parameters for preparing (PREP) and emptying (EMPTY)
  • 32.2 Exchange unit
    • 32.2.1 Maximum dosing and filling rate
    • 32.2.2 Default parameters for preparing (PREP)
  • 32.3 Stirring rate
  • 32.4 Balance
  • 32.5 Result variables as parameter setting
  • 32.6 Electrode calibration with USB Sample Processors
  • 32.7 Stored buffer series for pH calibration
  • 32.8 Using AuditTrailViewer
    • 32.8.1 Installing AuditTrailViewer
    • 32.8.2 Opening the Audit Trail
    • 32.8.3 Contents of the Audit Trail
    • 32.8.4 Filtering the Audit Trail
    • 32.8.5 Exporting the Audit Trail
  • 32.9 Diagnosis
    • 32.9.1 LCD test
    • 32.9.2 Temperature monitoring
    • 32.9.3 Formatting an external storage medium
    • 32.9.4 Removing an external storage medium
    • 32.9.5 Adjusting the touch screen
    • 32.9.6 Testing the touch screen
    • 32.9.7 Software update (loading program versions and language files)
      • 32.9.7.1 Carrying out a software update
    • 32.9.8 Simulating titration curves
    • 32.9.9 Service
  • 32.10 Arithmetic algorithms in the Titrando
• 33 Technical specifications
  • 33.1 Touch screen
  • 33.2 Interfaces
  • 33.3 Power supply
  • 33.4 Safety specifications
  • 33.5 Electromagnetic compatibility (EMC)
  • 33.6 Ambient temperature
  • 33.7 Dimensions
• 34 Warranty (guarantee)
• 35 Accessories
• Index