1 introduction, 1 instrument description, Instrument description – Metrohm 815 Robotic Soliprep for LC User Manual

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1 Introduction

815 Robotic Soliprep for LC

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1

1 Introduction

1.1

Instrument description

The 815 Robotic Soliprep systems are automation systems with a multiple
variety of applications. They have been designed exclusively for usage in
factories and laboratories and cover a wide range of applications. Soliprep
systems can be used for automation purposes wherever a complex sample
preparation of solid substances is required, e.g. for pharmaceutical or food
analysis.

The Robotic Sample Processors, which have proven their worth for many
years, form the basis for a versatile system that has been expanded to include
opportunities for the dispersion, filtration and bottling of samples of all sorts.
The versatile concept can be expanded practically at will.

Thanks to the integration of high-performance communication interfaces
(USB, RS232), they can be incorporated seamlessly into a variety of instru-
ment systems, and not only those manufactured by Metrohm. Operation by
the high performance tiamo

™ or MagIC Net™ software ensures not only

user-friendly operation and programming of automation sequences, but
also allows 100% conformity for the entire automation system with FDA
(Federal Drug Administration) regulations. This applies in particular with
regard to the regulation 21 CFR Part 11, electronic records and signa-
tures
.

815 Robotic Soliprep for Liquid Chromatography

Dispersion, filtration, dilution and sample transfer

The universal automation system for sample preparation in instrumental
chromatography. A workstation equipped with a dispersion device is used
to shred the sample. The dispersion aggregate is cleaned in a special rinsing
station. The second workstation is equipped for sample transfer with a uni-
versal robotic arm with a Luer adapter. It is used for picking up syringe
needles (for aspirating the dispersed sample and bottling the filtrate in sealed
vials) and membrane filters (for filtering and injecting the sample in a capil-
lary).

Needles, filters are charged in replaceable inserts. The needles and filters are
automatically stripped off after use and disposed of in a waste container.

Two versatile dosing drives (800 Dosino) are used as an auxiliary device for
diluting the sample and for transferring the sample solution.

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