ITC VerifyNow System Platelet Reactivity Test - Manual (Page 87)

Page 83 14439.C 03/2013
Appendix - 11
VerifyNow System User Manual | USA
Term Description
Pouch The white test device package.
Power indicator
When power is on, a green LED indicator on the lower left corner of the keypad
remains illuminated.
PRU See P2Y12 reaction units.
ReoPro
Abciximab (trade name ReoPro ® ) is a platelet aggregation inhibitor mainly used
during and after coronary artery procedures like angioplasty to prevent thrombus
(blood clot) formation within the coronary artery. Its mechanism of action is
inhibition of the glycoprotein IIb/IIIa complex.
Sample well
A test device has of a sample well. The instrument automatically draws whole
blood into the test device from a sample collection tube in the sample well.
Staging well
Each test device has a staging well. The instrument heats the blood in the staging
well (except for the Aspirin test, which is heated in the mixing well).
Spot code
The spot code consists of printed black circles on the test device. It provides
information about the test device to determine which test is being performed and
the test device lot number.
Thienopyridine
Thienopyridines are a class of therapy that has significant antiplatelet effect
by inhibiting adenosine diphosphate (ADP)-mediated platelet activation.
Thienopyridines irreversibly inhibit ADP binding to the P2Y12 receptor on the
platelet surface. Clopidogrel (trade name Plavix ® - clopidogrel bisulfate) and
prasugrel (trade name Effient ® ) is a thienopyridine.
Thromboxane
A2
A potent platelet agonist, thromboxane A2 is released by activated platelets and
acts to cause vasoconstriction and amplify the platelet recruitment by binding to
thromboxane receptors on the surface of circulating platelets.
TRAP See iso-TRAP.
V1
The maximum vacuum level parameter reported during electronic quality control
diagnostics. See electronic quality control.
V2
The maximum leak rate parameter reported during electronic quality control
diagnostics. See electronic quality control.
VerifyNow
A platelet function test developed by Accumetrics. The VerifyNow system is a
whole blood, point-of-care test, which consists of a turbidimetric-based optical
detection instrument, single-use test devices, and associated quality controls.
Wet quality
control
WQC measures two levels of turbidimetric signal that verify the dynamic range of
the instrument. It verifies continued performance by checking that actual results
are within a standard range.
WQC See wet quality control.
WQC kit
A kit of 6 wet quality controls (for Level 1 or 2 WQC). Controls are formulated at
clinically relevant levels, and are individually packaged in tubes (Level 1 and 2)
and vials (Level 2).
11.5 Software Icons
The icons represent actions and prompt the operator during the activities to configure the instrument,
test patient samples, perform quality control, and troubleshoot. The following is a complete list of all
screen icons and what each symbol represents: