BINDER KBF LQC 240 - Manual (Page 17)

KBF LQC (E5.3) 07/2014 page 17/114
2. Unit description
The constant climate chambers KBF LQC are equipped with a multifunctional microprocessor display
controller with 2-channel technology for temperature and humidity and a digital display accurate to one-
tenth of a degree resp. 0.1% r.H. With its comprehensive program control functions, the MB1 display
program controller permits the high precision course of temperature and humidity cycles as well as con-
trolled exposition of the samples up to defined dose values.
With its microprocessor controlled humidifying and dehumidifying system the KBF LQC is a high-
precision climatic chamber. It completely meets the requirements of the stipulated stability and durability
test for pharmaceutical products:
•
Stability tests acc. to ICH guideline CPMP/ICH/2736/99 (Q1A)
• Photostability tests acc. to ICH guideline CPMP/ICH/279/95 (Q1B)
Furthermore, it permits simulating exactly and over long periods constant conditions for other applications
such as sample conditioning for material testing of paper, textiles, plastics, building materials, etc.
The APT.line™ preheating chamber system guarantees high level of spatial and time-based temperature
precision, thanks to the direct and distributed air circulation into the interior. The fan supports exact at-
tainment and maintenance of the desired temperature accuracy.
The function Light Quantum Control permits integration of UV intensity and luminous intensity inside the
usable volume. The optical sensors used according to the ICH guideline for stability and durability tests of
pharmaceutical products Q1B. Sensor measurement is to a great extent directionally independent, dif-
fused light is also weighted. The function Light Quantum Control permits apart from displaying the actual
values of UVA and the visible spectral range cumulative measurement of the light doses In Manual Mode
target dose values of UVA and the visible spectral range can be entered. When they are reached, the
UVA and cool white fluorescent tubes are automatically turned off and notifying and alarm messages are
released.
A resistance humidifying system humidifies the air. For this purpose, use deionized (demineralized) wa-
ter. The option BINDER Pure Aqua Service permits using the chamber with any degree of water hard-
ness.
The inner chamber, the pre-heating chamber and the inside of the doors are all made of stainless steel
V2A (German material no. 1.4301, US equivalent AISI 304). The housing is RAL 7035 powder-coated. All
corners and edges are also completely coated.
All unit functions are easy and comfortable to use thanks to their clear arrangement. Major features are
easy cleaning of all unit parts and avoidance of undesired contamination.
The efficient program controller is regularly equipped with a multitude of operating functions, additional
recorder and alarm functions. Programming of test cycles is easily done via the modern MB1 color-
display controller and is also possible directly from the computer via Intranet in connection with the com-
munication software APT-COM™ 3 DataControlSystem (option, chap. 17.1).
The constant climate chamber KBF LQC is regularly equipped with an Ethernet serial interface for com-
puter communication. As a system solution BINDER offers the combination of the constant climate
chamber with ICH compliant illumination and the function Light Quantum Control with the GLP/GMP
compliant software APT-COM™ 3. This comfortable communication software from BINDER permits net-
working up to 30 units and connecting them to a PC for controlling and programming, as well as record-
ing and representing temperature and humidity data. For further options, see chap.21.5.
The KBF LQC is equipped with four castors. Both front castors can be locked by brakes.
The chambers can be operated in a temperature range from 0 °C / 32°F up to 70 °C / 158°F (without light
cassettes) / from 10 °C / 50°F up to 60 °C / 140°F (with illumination) and in a humidity range of 10% r.H.
to 80% r.H. When at least one light sensor is plugged-in, the maximum temperature is automatically lim-
ited to 60 °C.
For the control ranges of temperature and humidity, see diagrams (chap. 13).