Interference compounds – INFICON Explorer Portable Gas Chromatograph User Manual

Page 310

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Assay 2 User Notes

308

The library has been determined for the Assay 2 standard method. If the method is
altered, the library is no longer valid. If the method is modified, a new library must
be created, identifying the compounds with their new retention times.

For example, if the column temperature is increased, the retention time in the
Column B library is no longer valid, since compounds will be eluting faster than
they would in the standard method. You would have to run the compounds with the
new settings and store the compounds in the library.

Interference Compounds

Gasoline and its mixture of components is a possible interference. Gasoline is not
part of Assay 2, but may be present in your samples. Gasoline will interfere with the
early eluting peaks such as MTBE, TAME, methanol and ethanol.

Compounds lighter than the sample compounds are not separated and will elute as
an early peak. The integration delay can be used to prevent this composite peak from
being included in the peak report as shown in Figure 28.

Figure 28 Gasoline as Run on Column B

If gasoline is present, you may want to modify some chromatographic or integration
settings to ensure the best possible separation and peak identification.

NOTE: Gasoline will not be well separated on your system.

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