Bio-Rad BioLogic Signal Import Module (SIM) - Manual (Page 24)

DESCRIPTION OF BIOLOGIC DUOFLOW SYSTEM SYSTEM OVERVIEW
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2.3 BIOLOGIC MAXIMIZER VALVE SYSTEM
The Maximizer enables buffer blending applications, doubles the accessible pump flow rate, and doubles
valving capacity to 6 low pressure valves and 6 high pressure valves. The Maximizer includes a separate
Maximizer mixer (see Section 2.4.2) and pH monitor (see Section 2.5.4).
• Proportioning valves on the Maximizer blend water, salt, and the conjugate acid and base of a buffer
to obtain a solution with a user-defined pH and salt concentration. One valve delivers an acid and
base and the other valve delivers a salt and water.
• Pre-defined Buffer Blending buffer systems are provided for virtually all common buffers used in
chromatographic applications. Additional user-defined buffers may be created using the BioLogic
software Buffer Editor feature. The Maximizer uses the buffer system information to determine the
amount of acid, base, water and salt to add to obtained the desired buffer composition and pH.
• When the Maximizer is set to local mode in the software Manual screen, it will not be under
DuoFlow system control. In local mode the Maximizer front panel controls are accessible and can be
used to prime the system, calibrate the pH and conductivity monitor, observe the status of each
device, and control the position of each Maximizer valve.
• The Maximizer is designed to operate under normal laboratory and coldroom conditions (4° - 40° C)
with all commonly used aqueous chromatographic buffers.
The Maximizer includes the following hardware and circuitry:
• Front panel: on/off switches; two 3-port, two position proportioning valves for automated buffer
blending; an LCD screen and membrane switches for controlling valve positions and calibrating the
pH probe and conductivity monitor.
• Rear panel: connectors that (with the exception of the UV detector) duplicate the connectors on the
Workstation. It is recommended that valves, peripheral devices, and flow cells be connected to the
Maximizer rather than the Workstation unless more valving capability is needed.