860 system performance characteristics, Glucose biosensor interfering substances – Bayer HealthCare Rapidlab 800 User Manual

Page 554

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EĆ28

800 Series Operator's Manual

860 System Performance Characteristics

All performance data presented in this section was generated using 860 systems.
The system used default correlation factors, and performed calibrations using the
default settings recommended by Bayer Diagnostics for optimum performance. All
reported values were corrected to 760 mmHg. The operating environment during
the collection of this data was normal room temperature (about 23

_C).

You should determine your own performance characteristics in your laboratory
with your 860 system.

Glucose Biosensor Interfering Substances

To test for interferences, serum was spiked with a potentially interfering substance
up to the test concentration shown in the following two tables. The interference was
calculated by comparing the spiked sample to an unspiked sample immediately
preceding it. To evaluate the interference from fluoride/oxalate, the blood was
drawn in grey-top tubes and compared to the glucose recovery in heparinized
blood.

Table E-23 lists substances that were found not to interfere with the glucose
measurement. At the concentrations listed, these compounds produced less than
6 mg/dL (0.3 mmol/L) error in the recovered glucose concentration.

Table EĆ23.āăSubstances Showing No Interference

Substance

Concentration Tested

Chlorpromazine

5 mg/dL

Dopamine

0.5 mg/dL*

Ethanol

350 mg/dL

Salicylate

50 mg/dL

Sodium Nitroprusside

70 mg/dL

Citrate

1000 U/dL

Heparin

20,000 U/dL

Acetoacetate

40 mg/dL

Ascorbate

6 mg/dL

(Continued)

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